On a remote island in the South Pacific a Russian science team led by a Dr. Vorka finds an inactive Annihilator base, which they unknowingly reactivate.

Max and Susan are finally married but soon find themselves in battle against the annihilators who are beginning to sweep across the globe destroying all in their path. The fate of the human race depends the unearthing and reprogramming of another annihilator –Ava and the defending of a base in Greenland to buy time in order to change the past.